pentobarbital will lower the level or effect of buprenorphine, prolonged-acting injection by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Sufferers who transfer to buprenorphine prolonged-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers should be monitored to make sure bu… Read More